Diagnostic Management of Blood Cultures in the Pre-Analytical and Post-Analytical Phases: Scope Review

Authors

  • Suelen Lopes Santos da Silva Ambrósio Universidade Federal do Rio de Janeiro
  • Karla Regina Oliveira de Moura Ronchini Universidade Federal Fluminense
  • Glaucia Ribeiro Gonçalves de Rezende Universidade Federal do Rio de Janeiro
  • Alexandre Sousa da Silva Universidade Federal do Rio de Janeiro

DOI:

https://doi.org/10.26694/repis.v11i1.6148

Keywords:

Drug Resistance, Microbial, Blood Culture, Bacteremia., Microbiology, Antimicrobial Stewardship

Abstract

Introduction: Diagnostic stewardship of blood cultures optimizes healthcare resources and promotes safe patient care. Its focus lies in the rational use of tests that support the appropriate use of antimicrobials. Objective: To map
the available scientific evidence on the practices adopted by healthcare professionals in the pre-analytical and post-analytical phases of blood cultures that contribute to the diagnosis of patients with bloodstream infection.Design: Scoping review according to the Joanna Briggs Institute. The PCC acronym was used to construct the research question. The review was conducted using the databases MEDLINE, SCOPUS, EMBASE, LILACS, and the gray literature BDTD, correlating the descriptors “Blood Culture,” “Bacteremia,” “Sepsis,” “Pre-Analytical Phase,” and “Critical Laboratory Values.” Data collection wascarried out in May 2024 with no language or date filters. Results: Of the 164 studies, 22 met the research objective. Practices in the pre-analytical phase: interventions regarding the indication for collection, number of samples, volume, and transport. Practices in the post-analytical phase: timely communication and support for result interpretation. Implications: The study identifies the practices adopted by healthcare professionals in the pre-analytical and post-analytical phases of blood cultures that align with the principles of diagnostic stewardship.

Author Biographies

Suelen Lopes Santos da Silva Ambrósio, Universidade Federal do Rio de Janeiro

Universidade Federal do Rio de Janeiro, Programa de Pós-graduação em Saúde e Tecnologia no Espaço Hospitalar. Rio de Janeiro, Rio de Janeiro, Brasil.

Karla Regina Oliveira de Moura Ronchini, Universidade Federal Fluminense

Universidade Federal Fluminense, Faculdade de Medicina. Rio de Janeiro, Rio de Janeiro, Brasil.

Glaucia Ribeiro Gonçalves de Rezende, Universidade Federal do Rio de Janeiro

Universidade Federal do Rio de Janeiro, Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, Rio de Janeiro, Brasil.

Alexandre Sousa da Silva, Universidade Federal do Rio de Janeiro

Universidade Federal do Rio de Janeiro, Programa de Pós-graduação em Saúde e Tecnologia no Espaço Hospitalar. Rio de Janeiro, Rio de Janeiro, Brasil.

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Published

2025-06-17

How to Cite

Ambrósio, S. L. S. da S., Ronchini, K. R. O. de M., Rezende, G. R. G. de, & Silva, A. S. da. (2025). Diagnostic Management of Blood Cultures in the Pre-Analytical and Post-Analytical Phases: Scope Review. Journal of Infection Prevention and Health, 11(1). https://doi.org/10.26694/repis.v11i1.6148

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Section

Revisão Integrativa/Sistemática

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